TABLE 4.
Time (h) | Ratioa |
||||
---|---|---|---|---|---|
Single IA AZ |
Repeated maternal i.v. AZ |
||||
AF | FP | AF | FP | MP | |
4 | 0.1 | 52.3 | 96.3 | 5.5 | |
12 | 0.8 | 371.3 | 14.4 | ||
36 | 0.7 | 184.1 | 598.3 | 897.8 | 20.3 |
72 | 2.2 | 283.9 | 168.3 | 366.9 | 72.3 |
120 | 11.7 | 1,185.1 | 143.8 | 215.2 | 27.4 |
Fetal liver AZ concentrations (ng/g) and AF, FP, and MP AZ concentrations (ng/ml). The 36-, 72-, and 120-h values are minimum AZ concentrations for repeated maternal i.v. AZ animals.