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Inhibitory concentrations of tested compounds against P. falciparum strains 3D7 and Dd2a
| Compound | IC (mean ±SD) (nM) of indicated compound for strain: |
|||
|---|---|---|---|---|
| 3D7 |
Dd2 |
|||
| IC50 | IC90 | IC50 | IC90 | |
| Chlorotonil A | 9.1 ± 3 | 13.34 ± 3.2 | 18.1 ± 8.6 | 28.5 ± 8.5 |
| Chloroquine | 5.2 ± 1.2 | 8.2 ± 2.3 | 160.4 ± 62.1 | 228.6 ± 66.4 |
| Artesunate | 2.4 ± 1.3 | 7.5 ± 4.6 | 1.3 ± 0.2 | 1.8 ± 0.2 |
Each value is the mean inhibitory concentration of at least 3 independent experiments performed in duplicate.
