TABLE 1.
Strain | Collection date (day/mo/yr) | Source | Resistance (MIC [mg/liter]) |
|||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ceftaroline | Clindamycin | Daptomycin | Erythromycin | Levofloxacin | Linezolid | Methicillin | Minocycline | Penicillin G | Rifampin | Tetracycline | Telavancin | TMP-SMX | Vancomycin | |||
TMHS-3125 | 1/21/2013 | Sputum | R (>32) | R (>2) | S (1) | R (>4) | NP | R (>4) | R (>2) | S (2) | R (>1) | S (≤0.5) | S (2) | NP | S (≤0.5/9.5) | S (1) |
TMHS-3957 | 3/21/2013 | Sputum | S (1) | R (>2) | S (1) | R (>4) | NP | R (>4) | R (>2) | S (2) | R (>1) | S (≤0.5) | S (0.5) | NP | S (≤0.5/9.5) | S (1.5) |
TMHS-4147 | 3/28/2013 | Sputum | S (1) | R (>2) | S (1) | R (>4) | NP | R (>4) | R (>2) | S (≤1) | R (>1) | S (≤0.5) | S (0.5) | NP | S (≤0.5/9.5) | S (1.5) |
TMHS-4519 | 5/9/2013 | Sputum | I (1.5) | R (>2) | S (1) | R (>4) | NP | R (>4) | R (>2) | S (≤1) | R (>1) | S (1) | S (2) | NP | S (≤0.5/9.5) | S (1) |
TMHS-5006 | 6/19/2013 | Blood | R (>32) | R | NS (1.5) | R | R | R | R | S | R | S | S (1.5) | 0.19 | R | S (1) |
TMHS-5007 | 6/20/2013 | Sputum | R (>32) | R (>2) | S (1) | R (>4) | NP | R (>4) | R (>2) | S (≤1) | R (>1) | S (≤0.5) | S (1.5) | NP | S (≤0.5/9.5) | S (1) |
Results for ceftaroline, telavancin, tetracycline, vancomycin, and daptomycin were determined by Etest. All other antibiotics were tested with the BD Phoenix system, except for tests with TMHS-5006 for which MICs are not provided, for which the Kirby-Bauer disc diffusion method was used. S, susceptible; I, intermediate; R, resistant; NS, nonsusceptible; NP, not performed. CLSI breakpoints for ceftaroline were used. No susceptible, intermediate, or resistant result is listed for telavancin, as CLSI breakpoints for telavancin have not been established. TMP-SMX, trimethoprim-sulfamethoxazole.