TABLE 2.
Compound ID | IC90 (μM) BTG | MIC (μM) based on: |
|
---|---|---|---|
BTG | LORA | ||
2 | 0.98 | 3.13 | 68.40 |
3 | 7.87 | 25.00 | 64.76 |
4 | 0.43 | 1.56 | 82.25* |
7 | 0.87 | 3.13 | 140.83* |
8 | 12.76 | 25.00 | 64.60 |
19 | >100 | NA | 41.82* |
20 | >100 | NA | 27.14* |
21 | >100 | NA | 30.17* |
22 | ND | ND | 18.13* |
23 | >100 | NA | 25.24* |
RMP | 0.03 | 0.04 | 1.90 |
INH | 0.2 | 0.31 | >934* |
PA-824 | 1.34* |
Values are averages of duplicate measurements. NA, not applicable; ND, not determined. *, the compound was tested at the Institute of TB Research at the UIC.