TABLE 4.

MICs and MFCs in YPD in the background of strains expressing resistance mechanisms

Strain	Relevant characteristic or genotype	MIC (μg/ml)			MFC (μg/ml)
		24 h	48 h	72 h	24 h	48 h	72 h
SC5314	CAS5/CAS5	0.5	0.5	>64	>64	>64	>64
ERG11K143R	ERG11K143R::FRT/ERG11K143R::FRT CAS5/CAS5	4	8	8	4	8	8
ERG11K143R cas5Δ/Δ	ERG11K143R::FRT/ERG11K143R::FRT cas5Δ::FRT/cas5Δ::FRT	4	4	4	4	4	4
MRR1P683S	MRR1P683S::FRT/MRR1P683S::FRT CAS5/CAS5	8	16	>64	>64	>64	>64
MRR1P683S cas5Δ/Δ	MRR1P683S::FRT/MRR1P683S::FRT cas5Δ::FRT/cas5Δ::FRT	8	8	8	8	8	8
TAC1G980E	TAC1G980E::FRT/TAC1G980E::FRT CAS5/CAS5	8	16	>64	>64	>64	>64
TAC1G980E cas5Δ/Δ	TAC1G980E::FRT/TAC1G980E::FRT cas5Δ::FRT/cas5Δ::FRT	8	16	16	16	16	16