FIG 3.

Spectrum of activity. (A) CFU of strain 98-37-09 grown in human serum supplemented with 0.125 μg ml⁻¹ ciprofloxacin in the absence or presence of 1× the MEC of the putative efflux pump inhibitor ST009675 (2 μg ml⁻¹), ST058165 (32 μg ml⁻¹), or ST060273 (32 μg ml⁻¹); error bars indicate the standard deviations. (B) Mean CFU measures ± standard deviations for P. aeruginosa PAO1 following incubation in LB or serum with or without the efflux pump inhibitor PAβN, ST009675 (2 μg ml⁻¹), or ST060273 (32 μg ml⁻¹) supplemented with 0 to 2 μg ml⁻¹ of ciprofloxacin. (C) Structures of ABEPI1 (ST009675) and ABEPI2 (ST060273).