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Mutation of the embC-embA IGR in M. tuberculosis clinical strains
| Mutation sites | Mutation pattern | No. of strains | MGIT EMB DST resulta | Median MIC, μg/ml (interquartile range [%]) |
|---|---|---|---|---|
| −8 | C-T | 1 | R | 4 (4–4) |
| −11 | C-A | 6 | R | 8 (2–8) |
| C-T | 1 | R | 4 (4–4) | |
| −12 | C-T | 14 | R | 4 (4–8) |
| C-T | 2 | S | 4 (4–4) | |
| −16 | C-G | 12 | R | 8 (2–16) |
| C-T | 12 | R | 4 (4–8) | |
| C-T | 2 | S | 4 (4–4) | |
| C-A | 3 | R | 8 (8–8) | |
| −27 | T del | 1 | R | 2 (2–2) |
| −41 | A del | 3 | R | 8 (8–8) |
R, resistance; S, susceptibility.
