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Resistance to compounds that target the bc1 complex
| Protein | qcrB mutation | Fold resistance to compound: |
||||
|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | ||
| Qcr1 | A317V | >128 | 940.0 | >22 | 16.0 | >11 |
| Qcr2 | M342T | 24.1 | 78.0 | 8.3 | 8.0 | 1.3 |
| Qcr3 | W312G | 94.9 | 313.0 | >22 | 8.0 | >11 |
| Qcr4 | A396T | 5.9 | 7.0 | 16.1 | 6.1 | 5.3 |
| Qcr5 | M342I | 32.1 | 30.0 | >22 | 3.0 | 0.3 |
| Qcr6 | A317T | 8.0 | 60.0 | 21.7 | 11.8 | >11 |
| Qcr7 | S182P | 48.7 | 20.0 | >22 | 8.0 | >11 |
