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. 2014 Dec;58(12):7390–7397. doi: 10.1128/AAC.03337-14

TABLE 2.

SNPs identified in Pfmrp2 by sequencing the Thai isolates

Chromosome positiona Nucleotide position Nucleotide change Amino acid position Amino acid change Frequency (proportion) Location
1198644 561 T → A 187 Synonymous 0.02 (1/46) TM2
1198610*# 595 C → G 199 L → V 1.00 (46/46) TM2
1198321 884 C → G 295 T → R 0.02 (1/46) loop
1198275 930 G → T 310 L → F 0.02 (1/46) loop
1198224 981 C → T 327 Synonymous 0.02 (1/46) loop
1197428*§ 1777 A → G 593 N → D 0.07 (3/46) NBD1
1197341* 1864 A → G 622 N → D 0.22 (10/46) NBD1
1197064*§# 2141 A → T 714 K → I 1.00 (46/46) NBD1
1196808*§ 2397 C → T 799 Synonymous 0.39 (16/41) NBD1
1195791*§ 3414 T → C 1138 Synonymous 0.20 (9/44) NBD1
1194626*# 4579 T → A 1527 S → T 1.00 (46/46) TM9
1194614*# 4591 C → A 1531 L → I 1.00 (46/46) TM9
1194093 5112 T → C 1704 Synonymous 0.02 (1/46) NBD2
1193954 5251 A → T 1751 N → Y 0.09 (3/34) NBD2
1193947§ 5258 T → C 1753 F → S 0.07 (3/46) NBD2
1193882 5323 A → G 1775 I → V 0.14 (5/36) NBD2
1193861 5344 A → T 1782 M → L 0.02 (1/46) NBD2
1193820 5385 A → T 1795 Synonymous 0.08 (3/37) NBD2
a

Symbols: *, SNP previously registered with PlasmoDB; §, SNP previously found by deep sequencing of 227 samples from Africa, Asia, and Oceania (30); #, SNP previously described in reference 31.