. 2014 Dec;58(12):7565–7569. doi: 10.1128/AAC.03630-14

TABLE 2.

Combination indices for MVC, VVC, and VCH-286 against the R5 viruses HIV-1_BAL and HIV-1_CC1/85^a

Virus	Drug combination	CI₅₀	SD	CI₇₅	SD	CI₉₀	SD	Interpretation^b
HIV-1_BAL	MVC + VCH-286	0.76	0.05	0.56	0.03	0.41	0.08	Synergy
	MVC + VVC	9.53	0.629	7.49	0.377	5.61	0.53	Antagonism
	VVC + VCH-286	0.96	0.06	1.055	0.007	1.08	0.03	Additive
HIV-1_CC1/85	MVC + VCH-286	0.61	0.01	0.50	0.002	0.43	0.014	Synergy
	MVC + VVC	10.17	0.7	4.22	0.54	1.86	0.68	Antagonism
	VVC + VCH-286	0.68	0.23	1.91	0.098	2.22	0.42	Antagonism

Data are presented as the means from two independent experiments (three replicates per condition for each experiment) ± standard deviations (SD). The ranges of doses used for MVC, VVC, and VCH-286 were as follows: 0.0128, 0.064, 0.32, 1.6, 8, 40, 200, and 1,000 nM.

Combination index (CI) interpretation: <1, synergy; 1, additive; and >1, antagonism.