TABLE 4.
Prevalence of polymorphisms at NS5B positions important for BMS-791325 resistance
| Genotype (no.)a | Residue(s)/polymorphism(s) at NS5B position (% of sequences): |
||
|---|---|---|---|
| 494 | 495 | 499 | |
| 1a (384) | V (99.7), A (0.3) | P (100) | A (97.1), T (2.3), V (0.5) |
| 1b (763) | V (100) | P (100) | V (85.7), A (11), T (3), I (0.3) |
| 2a (31) | A (100) | P (100) | A (61.3), V (29), T (9.7) |
| 2b (27) | A (96.3), V (3.7) | P (100) | A (100) |
| 3a (44) | C (100) | P (100) | A (100) |
| 4a (25) | V (100) | P (100) | A (100) |
| 5a (4) | V (100) | P (100) | A (100) |
| 6a (22) | V (72.7), A (27.3) | P (95.5), L (4.5) | A (100) |
a
Numbers in parentheses are the numbers of GT1 to -6 NS5B sequences in the European HCV database with the indicated amino acid.