TABLE 1.

Levels of caspofungin at different times after intravitreal injection of 50 μg/0.1 ml in rabbits

Time	Caspofungin concn (μg/ml) in the vitreous (n = 4)a
10 min	13.98 ± 0.87
1 h	6.06 ± 1.76
2 h	4.71 ± 2.03
4 h	3.39 ± 0.42
8 h	2.98 ± 0.57
16 h	2.04 ± 0.94
24 h	0.47 ± 0.15
48 h	Undetectable

^aValues are means ± standard deviations. Caspofungin in all aqueous samples was below the detection limit (0.1 μg/ml) after injection.