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Histopathological alterations defined as inflammatory lesion scores induced by ESBL-producing or non-ESBL-producing E. coli strains at the 1st, 2nd, and 6th postinfection day. All mice infected with ESBL- and non-ESBL-producing strains were treated with ceftriaxone. Lesion scores of histopathological alterations are defined in Materials and Methods. An asterisk denotes a significant difference between non-ESBL and ESBL producers at day 6.
