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. 2014 Dec;58(12):7102–7111. doi: 10.1128/AAC.03974-14

FIG 8.

FIG 8

Photomicrographs from pairs of consecutive renal sections of mice infected with ESBL-producing bacteria with (B1 and B2) or without (A1 and A2) ceftriaxone (CRO) treatment. In the left panels, sections are stained with H&E (A1 and B1). In the right panels, sections are immunohistochemically labeled for IL-6 (A2 and B2). Numerous inflammatory cells (mainly neutrophils) infiltrating the tubules of renal medulla (arrows in A1) are positive for IL-6 (arrows in A2). Inflammatory cells located within the renal medulla and uroepithelium, adjacent to the pelvis (arrows in B1), are immunoreactive for IL-6 (arrows in B2).