FIG 3.
Susceptibilities of BVDUr and ACVr MHV-68 clones to nucleoside analogs, acyclic nucleoside phosphonates, and PFA. The data are presented as dot plots of the EC50 (μM) for the drug-resistant clones versus the EC50 for the wild-type (WT) clones. If the fold resistance (ratio of EC50 for mutant virus to EC50 for WT virus) was >1, the value of the ratio of EC50 for the mutant to EC50 for the WT is indicated at the top of the graph. EC50s were determined by CPE reduction assays, and horizontal bars indicate the mean values for a representative clone tested in three independent experiments.