TABLE 3.
Effect of pretreatment with 5-nitrouracil on the sensitivity of H. contortus larvae to naphthalophos
| 5-NU concn (mM) | Naphthalophos IC50 (μM)a | Synergism ratiob |
|---|---|---|
| 0 | 0.98 ± 0.14 A | |
| 0.125 | 0.72 ± 0.05 AB | 1.4 |
| 0.25 | 0.72 ± 0.06 AB | 1.4 |
| 0.5 | 0.49 ± 0.20 B | 2.0 |
| 1.0 | 0.31 ± 0.07 B | 3.2 |
| 2.0 | 0.34 ± 0.04 B | 2.9 |
a
Values are means ± SE (n = 3) from separate experiments with triplicate assay wells at each of a range of naphthalophos concentrations. Naphthalophos IC50s followed by the same letter are not significantly different (P = 0.05).
b
Naphthalophos IC50 in the absence of 5-NU/naphthalophos IC50 in the presence of 5-NU.