Table 2.
Univariate variables of in-hospital mortality after infant heart transplantation*
| Survived (n = 648) | Died (n = 82) | P value | |
|---|---|---|---|
| Age (mo) | 3.9 (1.8–6.8) | 2.5 (1.1–5.3) | .004 |
| Weight (kg) | 5.0 (3.6–6.0) | 4.0 (3.2–5.1) | <.001 |
| Donor weight (kg) | 7.0 (5.0–10.0) | 6.0 (4.0–8.0) | .003 |
| Donor/recipient weight ratio | 1.5 (1.1–1.9) | 1.4 (1.1–1.9) | .7 |
| BSA | 0.28 (0.23–0.32) | 0.24 (0.21–0.3) | .001 |
| Donor/recipient BSA ratio | 1.31 (1.08–1.57) | 1.26 (1.04–1.57) | .66 |
| Ischemic time | 3.8 (3.1–4.6) | 4.1 (3.1–4.7) | .12 |
| Female sex | 299 (46%) | 32 (39%) | .24 |
| Nonwhite race | 240 (37%) | 25 (30%) | .27 |
| Blood type | .42 | ||
| Identical | 475 (73%) | 55 (67%) | |
| Compatible | 127 (20%) | 19 (23%) | |
| Incompatible | 46 (7%) | 8 (10%) | |
| PRA > 10% | 40 (15%) | 2 (7%) | .39 |
| Cardiac diagnosis | <.001 | ||
| CHD | |||
| Repaired | 153 (24%) | 41 (50%) | |
| Unrepaired | 138 (21%) | 17 (21%) | |
| Unrepaired on PGE | 104 (16%) | 9 (11%) | |
| Cardiomyopathy | 212 (33%) | 12 (15%) | |
| Other | 41 (6%) | 3 (4%) | |
| Prior sternotomy | 82 (29%) | 19 (56%) | .003 |
| ECMO support | 65 (10%) | 29 (35%) | <.001 |
| Ventilator support | 176 (27%) | 16 (20%) | <.001 |
| Neither ECMO nor ventilator | 407 (63%) | 16 (20%) | <.001 |
| VAD support | 21 (3%) | 1 (1%) | .50 |
| Dialysis support | 7 (1%) | 13 (16%) | <.001 |
| Creatinine clearance < 40 mL · min−1 · m−2 | 106 (17%) | 35 (47%) | <.001 |
| BSI ≤ 2 wk before transplant | 176 (29%) | 36 (47%) | .001 |
BSA, Body surface area; PRA, panel of reactive antibodies; CHD, congenital heart disease; PGE, prostaglandin E; ECMO, extracorporeal membrane oxygenation; VAD, ventricular assist device; BSI, bloodstream infection.
*
All clinical variables defined at the time of heart transplantation.