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. 2014 Nov 16;2014:145129. doi: 10.1155/2014/145129

Table 1.

MCL and FL composite lymphomas.

Case number Age Involvement Immunohistochemistry staining   Treatment Follow-up Ref
Gender
1 66 F Waldeyer ring
Tonsil
Pharyngeal wall
Lingual tonsil
Nasal cavity
MCL: CD5+, CD20+, IgD+, cyclinD1+, Bcl-2+, CD3−
FL: CD2+, CD10+, Bcl-2+, Bcl-6+, CD5−
Corticosteroid PET scan every 3–6 months [2]

2 M Ocular adnexa NA NA Poor prognosis mentioned [3]

3 84 F Spleen FL: CD20+, CD23+, Bcl-6+, CD5−, CD43−, Bcl-2−
MCL: cyclinD1+, CD5−
Splenectomy
Patient refused additional treatment
9 months after splenectomy, CT scan showed intra-abdominal lymphadenopathy and patient died from unknown cause 13 months later [4]

4 70 F Cervical LN
Inguinal LN
CD20+, CD3−, cyclinD1−
50% of B-cell expressed CD5 (MCL)
30% of B-cell expressed CD10 (FL)
No chemotherapy CT of chest and abdomen showed no evidence of lymphadenopathy or hepatosplenomegaly [5]

5 65 M Inguinal LN FL: CD20+, CD79a+, CD10+, Bcl-2+, CD5−, CD230, cyclinD1−, p27+
MCL: CD20+, CD79a+, CD5+, CD10−, CD23−, cyclinD1+, p27−
Interfollicular areas mostly CD5+ showing distinct cylinD1 staining
Splenectomy MCL caused disease progression into spleen. One year after splenectomy, it achieved stable disease [6]

6 58 F Mesenteric LN
Small bowel
MCL: CD5+, CD20+, CD43+
FL: CD10+, CD20+, p27+
22 cycles of chemotherapy over 2 years Complete remission [7]