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Table 2.

Scoring and distribution of glomerular and tubular lesions in the groups under study at the final time

Rat groups
Young (n=8)
Old (n=7)
Scoring and distribution of glomerular and tubular lesions
Absent Mild (<25%) Moderate (25–50%) Severe (>50%)
Glomerular Lesions
Thickening of CB Young 8 (100%) 0 0 0
Old 2 (28,6%) 4 (57,1%) 1 (14,3%) 0
Hyalinosis of the vascular pole Young 8 (100%) 0 0 0
Old 0 (0 %) 7 (100%) 0 0
Glomerular atrophy Young 8 (100%) 0 0 0
Old 7 (100%) 0 0 0
Dilatation of the Bowman’s Space Young 8 (100%) 0 0 0
Old 5 (71,4%) 2 (28,6%) 0 0
Hypercellularity Young 8 (100%) 0 0 0
Old 2 (28,6%) 4 (57,1%) 1 (14,3%) 0
Tubular Lesion
Hyaline cylinders Young 8 (100%) 0 2 (28,5%) 0
Old 0 5 (71,4 %) 0 0
TBM irregularity Young 8 (100%) 0 0 0
Old 3 (42,9%) 1 (14,3%) 3 (42,9%) 0
Tubular calcification Young 8 (100%) 0 0 0
Old 7 (100%) 0 0 0
Interstitial fibrosis and tubular atrophy (IFTA) Young 8 (100%) 0 0 0
Old 0 7 (100%) 0 0
Interstitial Inflammatory infiltration Young 8 (100%) 0 0 0
Old 0 5(71,4%) 2 (28,5%) 0
Vacuolar Tubular Degeneration Young 0 8 (100%) 0 0
Old 0 0 7 (100%) 0