Table 3. Clinical EAE in actively immunized mice treated with α-NETAa.
Treatment group | Mean day of onset (SEM)b | Incidence by day 27 post-immunization |
vehicle | 10.6 (0.7) | 24/25 (96%) |
α-NETA | 19.6 (1.2)*** | 17/24 (71%)* |
Data are pooled from three independent experiments with each experiment consisting of 7–10 mice per group.
*p<0.05, as determined by Fisher's exact test;
***p<0.001, as determined by Mann-Whitney U test.
Determined only for animals that developed EAE.