Table 7. Clinical EAE in actively immunized CMKLR1 KO mice treated with α-NETAa.
Treatment Group | Mean day of onset (SEM)b | Incidence by day 20 post-immunization |
vehicle | 11.7 (1.0) | 12/15 (80%) |
α-NETA | 14.3 (1.5)ns | 6/15 (40%)ns |
Data are pooled from two independent experiments with each experiment consisting of 7–8 mice per group.
Determined only for animals that developed EAE.
: not significant (p = 0.18) by Students t test for mean day of onset or by Fisher's exact test for day 20 incidence (p = 0.06).