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. 2014 Dec 1;9(12):e113183. doi: 10.1371/journal.pone.0113183

Figure 3. Experimental Design.

Figure 3

A.) Experimental Setup for CCI-779 or CQ injections and tissue collection for analysis. B.) On day 0 FVB wild-type mice were either unirradiated or treated with a single 5-Gy dose of targeted head and neck radiation. Letters above treatment groups are used to signify statistical significance; treatment groups with the same letters are not significantly different from each other. Significant differences (p<0.05) were determined using an ANOVA followed by a post-hoc Bonferroni multiple-comparison test. Data are presented as the mean ±SEM. Stimulated salivary flow rates were determined as described in Materials and Methods section on day 3. N≥10/treatment group.