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. 2014 Dec 1;9(12):e113248. doi: 10.1371/journal.pone.0113248

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© 2014 Albrecht et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A) IgG levels in 134 human plasma samples against the recombinant NTS-DBL1α^It4var60 as detected by ELISA. Non immune indicates 20 non immune Swedish donors. Uncomplicated and severe indicate patients from Cameroon. B) Correlation between patient age and presence of antibodies in the plasma towards the recombinant NTS-DBL1α^It4var60 as measured by ELISA. C) Correlation between ability of the plasma sample to disrupt FCR3S1.2 iRBC rosettes and presence of antibodies towards to NTS-DBL1α^It4var60 as measured by ELISA. D) Correlation between ability of the sample to disrupt FCR3S1.2 iRBC rosettes and patient age. E) Correlation between ability of the plasma sample to recognize FCR3S1.2 iRBC surface as detected by FACS and presence of antibodies towards to NTS-DBL1α^It4var60 as measured by ELISA. F) Correlation between ability of the plasma sample to recognize FCR3S1.2 iRBC surface as detected by FACS and patient age.