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. 2014 Dec 1;9(12):e113338. doi: 10.1371/journal.pone.0113338

Figure 1. Disrupted B cell homeostasis in patients with chronic HCV infection.

Figure 1

(A) Gating strategy. (B) The frequencies of CD19+ B and (C) CD5+CD19+ B cells in 20 HCV-untreated patients (HCV, filled circles) and 20 healthy controls (HC, open circles). (D) The CD69, (E) CD86, (F) CD100 and (G) CD72 expression levels on B cells in HCV patients and healthy controls. The distribution of (H–I) CD100 and (J–K) CD72 in CD5+ and CD5- B cell subsets. The expression of CD100 on B cells was positively correlated with (L) ALT or (M) AST levels.