Table 1.
Showing changes in area percentage of collagen, α smooth muscle actin, mean number of PCNA positive cells/high power field (HPFs) and biochemical measurements (ALT, AST and albumin) in different groups
| Control group | CCL4 alone group | CCL4/MSCs group | CCL4/Recovery group | |
|---|---|---|---|---|
| Area percentage of collagen fibers (%) | 14.4±2.8 (■○) | 74.4±4.47 (*▲○) | 21.5±4.7 (■○) | 85.5±3.6 (*■▲) |
| Area percentage of α smooth muscle actin (%) | 14.67±3.33 (■○) | 41.43±2.1 (*▲○) | 18.4±3.8 (■○) | 58.26±4.09 (*■▲) |
| Number of PCNA/HPFs | 2.04±0.96 (▲) | 1.02±1.03 (▲) | 10.09±1.47 (*■○) | 1.21±0.03 (▲) |
| ALT (μ/L) | 57.4±6.8 (■○) | 112.6±16.1 (*▲) | 64.1±9.2 (■○) | 109.1±15.75 (*▲) |
| AST (μ/L) | 37.2±3.4 (■○) | 431.7±14.2 (*▲) | 46.5±4.7 (■○) | 434.7±16.15 (*▲) |
| ALBUMIN (g/dL) | 3.65±0.5 (■○) | 1.98±0.66 (*▲) | 3.73±0.34 (■○) | 1.72±0.53 (*▲) |
*
Significant difference from Control group,
■:
Significant difference from CCL4 alone group,
▲:
Significant difference from CCL4/MSCs group,
○:
Significant difference from CCL4/Recovery group.