Table 1. Comparison of left ventricular remodeling and function in Treg or PBS injected mice by 2-dimensional echocardiography 1 day after MI (baseline) and 4 weeks after first echo.
| Treg (n = 7) | PBS(n = 7) | p1 (repeated measures ANOVA) | |
| LVEDD, mm | |||
| Baseline | 3.7±0.1 | 3.4±0.08 | |
| 4 weeks | 3.9±0.2 | 4.2±0.14 | |
| p2(paired t-test) | 0.25 | 0.004 | 0.05 |
| LVESD, mm | |||
| Baseline | 2.7±0.1 | 2.3±0.07 | |
| 4 weeks | 2.8±0.2 | 3.2±0.19 | |
| P2(paired t-test) | 0.6 | 0.0009 | 0.006 |
| LVEDA, mm2 | |||
| Baseline | 11.05±0.5 | 10.32±0.5 | |
| 4 weeks | 12.11±1.09 | 13.35±0.5 | |
| P2(paired t-test) | 0.4 | 0.004 | 0.17 |
| LVESA, mm2 | |||
| Baseline | 6.07±0.52 | 4.06±0.3 | |
| 4 weeks | 6.3±0.8 | 8.18±0.7 | |
| P2(paired t-test) | 0.8 | 0.0005 | 0.004 |
| FS, % | |||
| Baseline | 26.26±3.6 | 32.96±2.9 | |
| 4 weeks | 27.93 ± 1.99 | 22.05±2.17 | |
| P2(paired t-test) | 0.7 | 0.007 | 0.03 |
| FAC, % | |||
| Baseline | 44.9±4.2 | 60.3±2.8 | |
| 4 weeks | 48.8±3.8 | 39.3±3.7 | |
| P2(paired t-test) | 0.5 | 0.0008 | 0.002 |
1. p in the right column reflect comparison of the differences between treatment and control groups over time. p based on 2-way repeated measures ANOVA.
2. p in the left columns are for the differences between baseline and 4-week measurements, based on paired t-test.
LVEDD = Left ventriculart end diastolic diameter; LVESD = Left ventricular end systolic diameter; LVEDA = Left ventricular end diastolic area; LVESA = Left ventricular end systolic area; FS = fractional shortening = [(LVDD (-) LVSD)/LVDD] x100; FAC = fractional area change = [(LVEDA-LVESA)/LVEDA]X100.