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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: J Biol Chem. 2007 Oct 12;283(1):294–300. doi: 10.1074/jbc.M708058200

FIGURE 4. Expression of calmodulin-binding deficient V100 exhibits dosage-dependent cellular toxicity in Drosophila photoreceptors.

FIGURE 4

A–C, pictures of a fly eye for control, loss, and gain of V100. All are morphologically normal. D–F, in contrast, overexpression of V100-WF causes mild developmental defects when expressed at low levels (by raising flies at 18 °C) and loss of photoreceptor neurons at high levels (27 °C). At the same high temperature, wild type v100 does not affect eye morphology (F). All effects were verified for three independent insertions of UAS-v100 and UAS-V100-WF.