Table 4.
Adjusted odds ratios and 95% CIs for Apgar Scores below the median stratified by age at exposure (all infants)a
| Apgar Scores at 1 minute | Apgar Scores at 5 minutes | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
||||||||||||
| Models |
<9 years at exposure
|
≥ 9 years at exposure
|
<9 years at exposure | ≥ 9 years at exposure | ||||||||
| N | OR | 95% C. I. | N | OR | 95% C. I. | N | OR | 95% C. I. | N | OR | 95% C. I. | |
|
|
||||||||||||
| Estimated PBBb (ppb) | ||||||||||||
| ≤ 1 | 76 | 1.00 | - | 67 | 1.00 | - | 76 | 1.00 | - | 67 | 1.00 | - |
| >1 - <2.5 | 115 | 3.03 | (1.29 - 7.08) | 72 | 1.60 | (0.58 - 4.42) | 115 | 3.93 | (1.15 - 13.42) | 72 | 1.73 | (0.56 - 5.31) |
| ≥2.5 | 106 | 3.54 | (1.48 - 8.47) | 87 | 1.82 | (0.72 - 4.63) | 106 | 3.70 | (1.06 - 12.87) | 87 | 1.75 | (0.60 - 5.06) |
| Enrollment PBBc (ppb) | ||||||||||||
| ≤ 1 | 70 | 1.00 | - | 57 | 1.00 | - | 70 | 1.00 | - | 57 | 1.00 | - |
| >1 - <4 | 123 | 2.41 | (0.98 - 5.93) | 76 | 0.84 | (0.33 - 2.12) | 123 | 2.12 | (0.66 - 6.76) | 76 | 1.25 | (0.40 - 3.95) |
| ≥4 | 132 | 3.33 | (1.37 - 8.12) | 97 | 0.94 | (0.41 - 2.15) | 132 | 2.66 | (0.84 - 8.44) | 97 | 1.19 | (0.41 - 3.48) |
a
Apgar scores below the median are <8 for 1 minute and <9 for 5 minutes; all models adjusted for infants born to the same mother
b
Estimated PBB is at the time of conception and calculated from an elimination model that adjusts for the mother’s body mass index at enrollment, smoking history, and pregnancy and breastfeeding histories.
c
Enrollment PBB models adjust for the mother’s body mass index at enrollment and excludes infants born to mothers who either reported being a smoker at enrollment or being pregnant since 1973.