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Liver injury was evaluated by (A) prothrombin time (PT), (B) blood ammonia level, (C) serum aspartate aminotransferase (AST) level, (D) serum alanine aminotransferase (ALT) level, (E) serum bilirubin level and renal impairment assessed by (F) serum creatinine. Data are expressed as median and range; statistical significance*p<0.05, **p<0.01, ***p<0.001 and ****p<0.0001.
