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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Nat Genet. 2014 Oct 5;46(11):1173–1186. doi: 10.1038/ng.3097

Figure 1. Regional association plots for loci with multiple association signals.

Figure 1

Panels a to d highlight examples of multiple signals after approximate conditional joint multiple-SNP analysis GCTA-COJO analysis. SNPs are shaded and shaped based on the index SNP with which they are in strongest LD (r2>0.4). Panels a–c show the majority of signals clustering in and around a single gene (ACAN, ADAMTS17, PTCH1, respectively) whereas panel d shows the multiple signals clustering through proximity.