Table 3. Multivariate analysis to identify factors predicting poor overall survival and disease-free survival of patients with hepatocellular carcinoma after curative hepatectomy.* .
Hazard Ratio | 95% CI | P | |
Overall Survival | |||
Diabetes mellitus | 1.482 | 1.044–2.104 | 0.028 |
AFP (≥400 ng/mL) | 1.603 | 1.108–2.319 | 0.012 |
Albumin (<35 g/L) | 1.634 | 1.035–2.577 | 0.035 |
GGT (≥50 U/L) | 1.891 | 1.245–2.872 | 0.003 |
Tumor capsule (Incomplete) | 1.553 | 1.073–2.247 | 0.020 |
Macrovascular invasion | 2.333 | 1.561–3.486 | <0.001 |
Tumor size (≥10 cm) | 1.112 | 1.012–1.223 | 0.027 |
Tumor number (≥3) | 2.431 | 1.596–3.702 | <0.001 |
Differentiation degree (Poorly) | 2.380 | 1.266–4.475 | <0.001 |
Disease-free survival | |||
Diabetes mellitus | 0.878 | 0.624–1.237 | 0.458 |
AFP ( ≥400 ng/mL) | 1.399 | 1.011–1.937 | 0.043 |
Albumin (<35 g/L) | 1.425 | 0.944–2.151 | 0.092 |
GGT (≥50 U/L) | 1.450 | 1.040–2.020 | 0.028 |
Tumor capsule (Incomplete) | 1.563 | 1.136–2.146 | 0.006 |
Macrovascular invasion | 1.638 | 1.124–2.388 | 0.010 |
Tumor size (≥10 cm) | 1.098 | 1.000–1.205 | 0.049 |
Tumor number (≥3) | 2.138 | 1.453–3.147 | <0.001 |
Differentiation degree (Poorly) | 1.814 | 1.102–2.984 | 0.019 |
*Calculated using data from all patients in the original cohort (without propensity score matching).
Abbreviations: AFP, alpha-fetoprotein; CI, confidence interval, GGT, γ-glutamyl transferase.