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. 2014 Dec 1;9(12):e114057. doi: 10.1371/journal.pone.0114057

Table 1. Characteristics of the included studies.

First author No. of patients(observation/control) Observation group Control group The main points Course of treatment The main outcomes
Tong (2013)[13] 86(44/42) Acupuncture plus rehabilitation Rehabilitation Cuanzhu (BL 2), Dangzhong(CV 17), Jianyu (LI 15), Yanglao (SI 16) 30minutes, once a day, 5 days for a week, 4 weeks Clinical efficacy Fugl-Meyer scale FIM
Weng (2013)[14] 120(60/60) Acupuncture plus rehabilitation Rehabilitation Penetration needling from Qianshencong (EX-HN 1) to Xuanli (GB 6), penetration needling from Baihui (GV 20) to Qubin(GB 7); Jiquan(HT 1), Chize (LU 5), Biguan (ST 31), Futu (ST 32) 30minutes, once a day, 5 days for a week, 4 weeks FMA
Du (2013) [15] 60(30/30) Acupuncture plus western medicine group Western medicine group Sibai (ST 2), Shuigou (DU 26), Jianyu (LI 15), Quchi (LI 11), Futu (ST 32), Zusanli (ST 36), Huangshu (KI 16), Tianshu(ST 25) 30–40minutes, once a day, 5 days for a week, 2 weeks Clinical efficacy NIHSS
Guo (2012) [16] 67(34/33) Acupuncture plus rehabilitation Rehabilitation Baihui (GV 20), Fengchi (GB 20), Shuigou (DU 26), Hegu (LI 4), Neiguan (PC 6), Zusanli (ST 36), Sanyinjiao (SP 6), Taichong(LR 3) 30minutes, once a day, 2 weeks NIHSS
Shen (2012)[17] 287(144/143) Acupuncture plus standard treatment Sham acupoints plus standard treatment Neiguan (PC 6), Shuigou (DU 26), Sanyinjiao (SP 6), Jiquan (HT 1), Weizhong(BL 40), Chize (LU 5) Once a day, 4 weeks NIHSS BI
Hsing 62(35/27) Scalp Subcutaneous needles at the projection of the motor, 30minutes, NIHSS
(2012)[18] electrical acupuncture stimulation Placebo electrical stimulation sensory, frontal and temporal associative areas of penfield homunculus in the scalp twice a week, 5 weeks BI
Shu 120(60/60) Acupuncture Control group Jianyu (LI 15), Quchi (LI 11), Shousanli (LI 10), 20minutes, once BI
(2011)[19] group Hegu (LI 4), Xuehai (SP 10), Liangqiu (ST 34), Zusanli (ST 36), Sanyinjiao (SP 6) a day, 10 treatment for one course, 3 courses FMA
Cheng 60(30/30) Acupuncture Conventional Zhongzhu (TE 3), Waiguan (TE 5) 30minutes, once NIHSS
(2011)[20] plus conventional treatment treatment a day, twenty treatment for one course, 2 courses BI
Wu (2011)[21] 80(40/40) Acupuncture plus routine Treatment Hegu (LI 4), Shousanli(LI 10), Neiguan (PC 6), Waiguan (TE 5), Jianyu (LI 15), Quchi (LI 11); Futu 30minutes, once every other day, Clinical efficacy NIHSS
treatment (ST 32), Zusanli (ST 36), Fenglong (ST 40), Yanglingquan (GB 34), Taichong (LR 3), Sanyinjiao (SP 6), Shenmai (BL 62), Zhaohai (KI 6) 10 times constitute a treatment course, 2 courses BI
Zhang (2011)[22] 58(29/29) Electro-needling plus routine treatment Routine treatment Jianyu (LI 15), Quchi (LI 11), Shousanli (LI 10), Hegu (LI 4), Biguana (ST 31), Futu (ST 32), Liangqiu (ST 34), Zusanli (ST 36), Fenglong (ST 40), Jiexi (ST 41) 30minutes, once a day, 6 days for a week, 2 weeks Fugl-Meyer scale
Lin (2009) [23] 56(37/19) Acupuncture plus western medicine treatment Western medicine treatment Shangjuxu (ST 37), Fenglong (ST 40), Zusanli (ST 36), Neiguan (PC 6), Sanyinjiao (SP 6), Shuigou (DU 26) 30minutes, once per day, 3 weeks Clinical efficacy
Li (2009)[24] 63(31/32) Acupuncture and routine treatment Routine treatment Baihui (GV 20), Lianquan (CV 23) and affected-sided Fengchi (GB 20), Jianyu (LI 15), Quchi (LI 11), Zusanli (ST 36), Sanyinjiao (SP 6) and Taichong (LR 3) 30minutes, once a day, 7 times constitute a course of treatment, 4 weeks Clinical efficacy
Zhang (2009)[25] 80(40/40) Acupuncture plus rehabilitation treatment Rehabilitation treatment Jianyu (LI 5), Quchi (LI 11), Hegu (LI 4), Yanglingquan (GB 34), Yinglingquan (SP 9), Zusanli(ST 36), Sanyinjiao (SP 6) 20minutes, once a day, 3 weeks Clinical efficacy Fugl-Meyer scale
Zhang (2008)[26] 90(45/45) Acupuncture group and Routine treatment Scalp motor area (MS 6), sensory area (MS 7), speech area, Baihui(GV 20), Fengchi (GB 20), 20minutes, once a day, Clinical efficacy NDS
routine treatment Quchi (LI 11), Hegu (LI 4), Zusanli (ST 36) and Taichong (LR 3) 10-treatment made up one course, 2 courses BI
Huang (2008)[27] 80(40/40) Back-shu point group and routine treatment Non-point group and routine treatment Feishu (BL 13), Xinshe (BL 15), Geshu (BL 17), Ganshu (BL 18), Danshu (BL 19), Pishu (BL 20), Wenshu (BL 21), Waiguan (SJ 5), Houxi (SI 3), Zusanli (ST 36), Xuanzhong (GB 39) 30minutes, once a day, 6-treatment for one course, 4 courses Clinical efficacy BI
Yang (2008)[28] 96(50/46) Acupuncture plus rehabilitation treatment Rehabilitation treatment Qihai (CV 6), Guanyuan (CV 4), Hegu (LI 4), Zusanli (ST 36), Sanyinjiao (SP 6) and Xuehai (SP 10) 30minutes, once a day, 1-month treatment made up a course Clinical efficacy
Guo (2007)[29] 88(46/42) Acupuncture plus routine treatment Routine treatment Baihui (GV 20) penetrating to Qubin (GB 7) on the affected side, Renzhong (GV 26), Lianquan (CV 23), Neiguan (PC 6), Quchi(LI 11), Hegu (LI 4), Xuehai (SP 10), Zusanli(ST 36), Fenglong (ST 40), Sanyinjiao (SP 6) and Taichong (LR 3) 30minutes, once a day, 5 times a week, 3 weeks Clinical efficacy
Feng (2007)[30] 60(30/30) Acupuncture plus routine treatment Routine treatment Bilateral Fengchi (GB 20), Wangu (GB 12) and Tianzhu (BL 10) 30minutes, once a day, 15 days as a course of treatment, 2 course Clinical efficacy
Rao (2006)[31] 40(20/20) Acupuncture plus routine treatment Routine treatment Neiguan (PC 6), Shuigou (DU 26), Sanyinjiao (SP 6) Once a day, 5 days for a week, 4 weeks BI
Schuler (2005)[32] 81(41/40) Acupuncture group Placebo group(surface electrodes on acupuncture points with visual stimulation) Needling of acupuncture points with electrical stimulation 30minutes, twice weekly for 4 weeks BI
Zhu (2005)[33] 80(40/40) Acupuncture plus routine treatment Routine treatment Baihui (GV 20), Fengchi (GB 20), Jiquan (HT 1), Neiguan (PC 6), Hegu (LI 4), Zusanli (ST 36), Taichong (LR 3), Taixi (KI 3), Fuliu (KI 7), Yinbai (SP 1) and Zuqiaoyin (GB 44) 20minutes, once a day, 12 days Clinical efficacy NDS
Xie 64(32/32) Electro-acupuncture Placebo Yuji (LU 10), Hegu (LI 4), Waiguan (SJ 5), 10–20minutes, NIHSS
(2004)[34] needle Shousanli (LI 10), Yanglinquan (GB 34), Zusanli once a day, FMA
treatment treatment (ST 36), Xuanzhong (GB 39), Taichong(LR 3) 7–10days for one course, 2–3 courses MBI
Liu (2001)[35] 160(120/40) Acupuncture plus routine treatment Routine treatment Baihui (GV 20), Dazhui (DU 14), Zusanli (ST 36), Shousanli (LI 10), Xuehai (SP 10), Quchi (LI 11) 30minutes, once a day, 6 days for a week, 2 months Clinical efficacy
Wu (2001) [36] 100(50/50) Scalp acupuncture treatment Medication treatment A needle was inserted into Baihui (GV 20) then advanced to Qianding (GV 21), another needle was penetrated from Shuaigu (GB 8) to Xuanli (GB 6) Once a day, 14 days for one course, 2 courses Clinical efficacy
Pei 86(43/43) Electro-acupuncture Routine Hegu (LI 4), Shousanli (LI 10), Quchi (LI 11), 20minutes, once CSS
(2001)[37] plus treatment Jianyu (LI 15), Sanyinjiao (SP 6), Fenglong (ST 40), a day, 5 days for BMF
routine treatment Zusanli (ST 36), Baihui(DU 20) and motor area of the scalp a week, 4 weeks BI

FMA: Fugl-Meyer Assessment, BFM: Brunnstrom-Fugl-Meyer (BFM test for determining the level of motor impairment), BI: Barthel Index, FIM: Functional independence measure, MBI: Modified Barthel Index, NIHSS: NHI Stroke Scale, DNS: Neurological Deficits Score, CSS: Chinese Stroke Scale(CSS for assessing the degree of neurological deficit).