Table 1. Comparative analysis of p53 Pro72Arg polymorphism status in SCCOT, ESCC and healthy control samples.
| Genotype distributiona | Allele distribution | ||||||
| Pro/Pro | Pro/Arg | Arg/Arg | Pc | Pro72 | Arg72 | Pc | |
| Controls (110) b | 26 (23.6%) | 53 (48.2%) | 31 (28.2%) | - | 105 (47.7%) | 115 (52.3%) | - |
| SCCOT (115) b | 44 (38.3%) | 48 (41.7%) | 23 (20%) | 0.051 | 136 (59.1%) | 94 (40.9%) | 0.019 |
| ESCC (82) b | 20 (24.4%) | 46 (56.1%) | 16 (19.5%) | 0.363 | 86 (52.4%) | 78 (47.6%) | 0.361 |
a
χ2 test p values for deviation from Hardy-Weinberg equilibrium are 0.71, 0.18 and 0.37 for controls, SCCOT and ESCC, respectively.
b
Number in parenthesis indicates total number of samples.
c
p is from χ2 test performed for comparison of SCCOT or ESCC with controls.