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. 2014 Dec 1;9(12):e114259. doi: 10.1371/journal.pone.0114259

Table 2. Subgroup meta-analysis of uric acid levels and adjusted risk of incident hypertension*.

Subgroup No. of included studies Heterogeneity test(I 2, P) Summary RR (95% CI)
Categorical data
Sex
Female 6 0.0%, P = 0.770 1.66 (1.46–1.88)
Male 12 68.3%, P<0.001 1.49 (1.31–1.68)
Ethnicity
Asian 7 68.8%, P = 0.004 1.53 (1.32–1.78)
Non-Asian 10 83.7%, P<0.001 1.45 (1.23–1.72)
Follow-up
<5 years 4 70.7%, P = 0.017 1.27 (1.12–1.45)
≥5 years 13 66.5%, P<0.001 1.57 (1.39–1.78)
Sample size
<3000 9 60.0%, P = 0.010 1.45 (1.24–1.70)
≥3000 8 87.1%, P<0.001 1.51 (1.29–1.76)
Continuous data
Sex
Female 5 21.4%, P = 0.278 1.12 (1.05–1.19)
Male 9 64.9%, P = 0.004 1.15 (1.08–1.21)
Ethnicity
Asian 7 91.8%, P<0.001 1.22 (1.10–1.34)
Non-Asian 8 52.4%, P = 0.040 1.14 (1.08–1.21)
Follow-up
<5 years 4 59.9%, P = 0.058 1.31 (1.16–1.48)
≥5 years 11 76.7%, P<0.001 1.14 (1.08–1.19)
Sample size
<3000 8 81.8%, P<0.001 1.20(1.09–1.32)
≥3000 7 78.2%, P<0.001 1.17 (1.10–1.24)

*The variables adjusted in each primary study were shown in Table S1.