Table 2. Subgroup meta-analysis of uric acid levels and adjusted risk of incident hypertension*.
Subgroup | No. of included studies | Heterogeneity test(I 2, P) | Summary RR (95% CI) |
Categorical data | |||
Sex | |||
Female | 6 | 0.0%, P = 0.770 | 1.66 (1.46–1.88) |
Male | 12 | 68.3%, P<0.001 | 1.49 (1.31–1.68) |
Ethnicity | |||
Asian | 7 | 68.8%, P = 0.004 | 1.53 (1.32–1.78) |
Non-Asian | 10 | 83.7%, P<0.001 | 1.45 (1.23–1.72) |
Follow-up | |||
<5 years | 4 | 70.7%, P = 0.017 | 1.27 (1.12–1.45) |
≥5 years | 13 | 66.5%, P<0.001 | 1.57 (1.39–1.78) |
Sample size | |||
<3000 | 9 | 60.0%, P = 0.010 | 1.45 (1.24–1.70) |
≥3000 | 8 | 87.1%, P<0.001 | 1.51 (1.29–1.76) |
Continuous data | |||
Sex | |||
Female | 5 | 21.4%, P = 0.278 | 1.12 (1.05–1.19) |
Male | 9 | 64.9%, P = 0.004 | 1.15 (1.08–1.21) |
Ethnicity | |||
Asian | 7 | 91.8%, P<0.001 | 1.22 (1.10–1.34) |
Non-Asian | 8 | 52.4%, P = 0.040 | 1.14 (1.08–1.21) |
Follow-up | |||
<5 years | 4 | 59.9%, P = 0.058 | 1.31 (1.16–1.48) |
≥5 years | 11 | 76.7%, P<0.001 | 1.14 (1.08–1.19) |
Sample size | |||
<3000 | 8 | 81.8%, P<0.001 | 1.20(1.09–1.32) |
≥3000 | 7 | 78.2%, P<0.001 | 1.17 (1.10–1.24) |
*The variables adjusted in each primary study were shown in Table S1.