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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Neuropharmacology. 2014 Sep 6;89:11–18. doi: 10.1016/j.neuropharm.2014.08.014

Figure 1.

Figure 1

Alterations in the BLA field potentials after soman-induced SE and protection by LY293558 treatment. A–D. Representative field potentials evoked in the BLA by paired-pulse stimulation of the external capsule, from control rats (n = 11, A), soman-exposed rats (black waveforms) at 24 hours (n = 11, B), 7 days (n = 11, C), and 30 days (n = 10, D) after exposure, and soman+LY293558 treated rats (red waveforms) at 24 hours (n = 9, B), 7 days (n = 8, C), and 30 days (n = 9, D) after exposure. Each trace is an average of 30 sweeps. In soman-exposed rats, the duration of the field potentials was prolonged (notice the slow decay of the waveforms); this was not observed in soman+LY293558 treated rats. E. Paired-pulse ratio (PPR) was significantly increased in soman-exposed rats, but not in soman+LY293558 treated rats. The PPR was significantly lower in the soman+LY293558 treated animals compared to the soman-exposed animals. *p < 0.05, **p < 0.01, ***p < 0.001 (One-Way ANOVA and Independent T-tests).