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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Neurobiol Learn Mem. 2014 Sep 6;0:49–57. doi: 10.1016/j.nlm.2014.08.016

Figure 4.

Figure 4

Posttraining intra-BLA infusions of clenbuterol enhance memory for the higher-arousing object recognition task (Without-Habituation) and dorsal hippocampal synaptic Arc protein expression. A.) Posttraining intra-BLA infusions of clenbuterol enhance memory for the novel object recognition task (Without-Habituation). Rats that received immediate posttraining intra-BLA infusions of clenbuterol (n=7; 4 ng/0.2 µL) had significantly higher discrimination indices during the retention test than those that received intra-BLA infusions of vehicle (n=8; p<.01). B.) Western blot analysis of Arc protein expression 45 min after training on the low-arousing object recognition task (Without-Habituation) and drug treatment. Memory-enhancing clenbuterol (n=5; 4 ng/0.2 µL) significantly increases Arc protein expression in dorsal hippocampal enriched synaptic tissue as compared to intra-BLA vehicle (n=7, p=.15). Representative blot images are shown underneath the graph. V=vehicle, C=clenbuterol. Data are presented as mean + SEM.