FIG. 5.
Survival curves of murine challenge with KIM6+ and mutants deficient in glpD and/or the glpABC operon. A. Intranasal inoculation with 4000 CFU (~6 LD50 KIM6+/pCD1Ap) n = 5 mice per group. B. Subcutaneous inoculation 200 CFU (~20 LD50 KIM6+/pCD1Ap) n = 10 mice per group. C. Intranasal inoculation with 4000 CFU (~10 LD50 KIM6+/pCD1Ap) n = 5 mice per group D. Subcutaneous inoculation 500 CFU (~50 LD50 KIM6+/pCD1Ap) n = 5 mice per group. Verification of proper inoculum was determined by CFU enumeration. P-values were calculated by log-rank test.