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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Alcohol. 2014 Sep 6;48(7):639–645. doi: 10.1016/j.alcohol.2014.09.002

Figure 4.

Figure 4

Repeated cycles of CIE exposure enhance operant self-administration. Shown are the mean ± SEM of responses (left graphs) and intake (g/kg) of ethanol (right graphs) for the experimental groups of mice subsequently used for examination of the effect of devaluation on self-administration (A) and extinction (B). For both groups of mice, baseline responding and intake are shown prior to initiation of CIE and after 4 cycles of CIE or air control exposure. The * indicates significant difference compared to respective control values (ANOVA with Newman-Keuls post hoc test; p < 0.05).