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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Alcohol. 2014 Sep 6;48(7):639–645. doi: 10.1016/j.alcohol.2014.09.002

Figure 6.

Figure 6

CIE-induced insensitivity to ethanol devaluation correlates with a reduction in ethanol intake. Shown is ethanol consumption (g/kg) for self-administration before and after ethanol or sham devaluation. Prior to devaluation, mice that had undergone 5 cycles of CIE showed enhanced ethanol intake compared to the air-exposed controls. After ethanol- or sham-devaluation, ethanol consumption in the air-exposed control group was sensitive to devaluation. In contrast, ethanol consumption in mice that had undergone CIE exhibited drinking that was not affected by devaluation. The * indicates significant increase of CIE versus CTL (t test, p < 0.05). The # indicates significant difference from respective non-devalued controls (ANOVA with Newman-Keuls post hoc test, p < 0.05)