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. Author manuscript; available in PMC: 2014 Dec 2.
Published in final edited form as: Transl Res. 2014 Jun 17;164(5):424–432. doi: 10.1016/j.trsl.2014.06.003

Fig 1.

Fig 1

Azilsartan medoxomil reverses established cerebrovascular remodeling in diabetes. Across the pressure range, lumen diameter is lower while wall thickness and wall: lumen ratio are greater in diabetic GK rats (A–C, *p<0.05). At 100 mmHg pressure point, lumen diameter at is similar across groups (B) but wall thickness (E) and wall:lumen ratio (F) are greater in diabetic rats (*p<0.05) and treatment restores these indices only in diabetic rats with no effect in control animals (E, **p=0.022; F, **p=0.0138; disease treatment interaction, #p<0.05 vs vehicle). Values are mean ± SEM, n=6–8/group.