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. Author manuscript; available in PMC: 2015 Nov 20.
Published in final edited form as: Int J Pharm. 2014 Aug 26;475(0):282–291. doi: 10.1016/j.ijpharm.2014.08.039

Table 3.

Actual drug loading and crystallinity of fibers electrospun from needle or wire electrodes.
Actual Drug Loadinga (wt%) Relative drug crystallinityb (%)
Needle Wire Needle Wire
0% TFV, pH 5 0 0 nd nd
0% TFV, pH 7 0 0 nd nd
10% TFV, pH 3 7.5 7.3 nd nd
10% TFV, pH 7 9.4 9.4 nd nd
60% TFV, pH 3 59.2 49.7 96.1 96.3
60% TFV, pH 7 52.4 51.9 nd 2.0
a

Actual drug loading represents average measured by dissolving meshes in citrate buffer (n=3).

b

Relative drug crystallinity was calculated from differential scanning calorimetry (DSC) thermograms and is reported as percentage of crystalline TFV in fibers relative to the heat of fusion of TFV drug in powder form, correcting for mass fraction of drug in sample. Nd=not detected.