Table 3.
Comparison between clinico-pathological features of MSI-H and MSS in colorectal cancer, n (%).
| Features | Total | MSI-H | MSS | P |
| Number of cases (%) | 207 | 15 (7.25) | 192 (92.7) | |
| Age (yr) | 66.2±12.4 | 69.7±14.8 | 65.9±12.2 | 0.2481 |
| Gender(male/female) | 139/68 | 8/7 | 131/61 | 0.3692 |
| Location of tumor | ||||
| Right colon | 37 (17.9) | 7 (46.7) | 30 (15.6) | 0.0053 |
| Left colon | 85 (41.1) | 2 (13.3) | 83 (43.2) | |
| Rectum | 85 (41.1) | 6 (40.0) | 79 (41.2) | |
| TNM stage | ||||
| I | 25 (14.2) | 1 (6.7) | 24 (12.5) | 0.7804 |
| II | 73 (36.8) | 6 (40.0) | 67 (34.9) | |
| III | 68 (31.6) | 6 (40.0) | 62 (32.3) | |
| IV | 41 (17.4) | 2 (13.3) | 39 (20.3) | |
| Invasive pattern | ||||
| Expanding | 52 (25.1) | 4 (26.7) | 48 (25.0) | 1.02 |
| Infiltrative | 155 (74.9) | 11 (73.3) | 144 (75.0) | |
| Grade of differentiation | ||||
| Well | 5 (2.4) | 0 | 5 (2.6) | <0.0013 |
| Moderate | 182 (87.9) | 9 (60.0) | 173 (90.1) | |
| Poor | 20 (9.7) | 6 (40.0) | 14 (7.3) | |
| Lymphovascular invasion | ||||
| Yes | 48 (23.2) | 1 (6.7) | 47 (24.5) | 0.2092 |
| No | 159 (76.8) | 14 (93.3) | 145 (75.5) | |
| Mucin component | ||||
| Yes | 29 (14.0) | 7 (46.7) | 22 (11.5) | 0.0012 |
| No | 178 (86.0) | 8 (53.3) | 170 (88.5) |
1
Student t test,
2
Fisher exact test,
3
Pearson χ2 test,
4
χ2 test with linear-by-linear association.