Table 3.

Longitudinal studies correlating dietary fiber with colorectal neoplasia

Reference	Location	Cohort	Follow-up period (yr)	Odds ratio of CRC comparing highest to lowest fiber intake groups	Dietary fiber protective
Fuchs et al 1999[24]	US	88 757 (women)	16	0.95 (95% CI 0.73-1.25)	No
Mai et al 2003[25]	US	45 491 (women)	8.5	0.94 (95% CI 0.71-1.23)	No
Lin et al 2005[26]	US	36 976 (women)	10	0.75 (95% CI 0.48-1.17)	No
Otani et al 2006[27]	Japan	86 412	10	Hazard ratio of lowest fiber intake group compared to highest group: 2.3 (95% CI 1.0-5.2)	No
Shin et al 2006[28]	China	73 314 (women)	5.7	1.1 (95% CI 0.6-1.8)	No

CRC: Colorectal cancer.