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. 2005 Mar 7;11(9):1273–1282. doi: 10.3748/wjg.v11.i9.1273

Table 1.

Differentially expressed genes in prewarning microarray of gastric cancer.

GenBank Number Description of gene
Highly expressed genes in gastric cancer
1 NM_001962 Homo sapiens ephrin-A5 (EFNA5)
2 XM_017384 Homo sapiens matrix metalloproteinase 7 (MMP7)
3 NM_008610 Mus musculus matrix metalloproteinase 2 (Mmp2)
4 NM_004995 Homo sapiens matrix metalloproteinase 14 (MMP14)
5 AF093573 Bos taurus angiopoietin-1 (ang-1)
6 AF004327 Homo sapiens angiopoietin-2
7 M11730 Human tyrosine kinase-type receptor (HER2)
8 U13948 Human zinc finger/leucine zipper protein (AF10)
9 XM_049646 Homo sapiens similar to octamer-binding transcription factor 3B (OCT-3B)
10 XM_055784 Homo sapiens fibroblast growth factor 2 (basic) (FGF2)
11 XM_056035 Homo sapiens proliferating cell nuclear antigen (PCNA)
12 L24203 Homo sapiens ataxia-telangiectasia group D-associated protein
13 XM_087201 Homo sapiens similar to RED protein, IK cytokine
14 X00663 Human mRNA fragment for epidermal growth factor (EGF) receptor
15 NM_002607 Homo sapiens platelet-derived growth factor alpha polypeptide (PDGFA)
16 XM_165656 Homo sapiens matrix metalloproteinase 2 (MMP2)
17 NM_005918 Homo sapiens malate dehydrogenase 2, NAD (mitochondrial) (MDH2)
18 AF503165 Homo sapiens HUS1 checkpoint homolog (HUS1) gene
19 XM_045667 Homo sapiens antigen identified by monoclonal antibody Ki-67 (MKI67)
20 XM_050913 Homo sapiens frequently rearranged in advanced T-cell lymphomas (FRAT1)
21 XM_032866 Homo sapiens signal transducer and activator of transcription 5A (STAT5A)
22 NM_004103 Homo sapiens protein tyrosine kinase 2 beta (PTK2B)
23 XM_008355 Homo sapiens membrane protein, palmitoylated 2 (MPP2)
24 L18920 Human MAGE-2 gene exon 2, 3, 4
25 M12174 Human ras-related rho
26 NM_012333 Homo sapiens c-myc binding protein (MYCBP)
27 BC016514 Homo sapiens, similar to translocated promoter region (to activated MET oncogene)
28 NM_004324 Homo sapiens BCL-2 associated X protein (BAX)
29 Z26580 cyclin A
30 D45906 LIMK-2
31 D21255 OB-cadherin-2
32 X54925 Type I interstitial collagenase
33 X05232 Stromelysin, matrix metalloproteinase 3
34 M22612 Human pancreatic trypsin 1 (TRY1)
35 XM_055254 Homo sapiens fibronectin 1 (FN1)
36 AF081127 Danio rerio fibronectin (fn2)
37 M15796 Human cyclin protein gene
38 HSFIBEDA Human fibronectin gene ED-A region
39 HSU66406 Human putative EPH-related PTK receptor ligand LERK-8 (Eplg8)
40 AF068846 Homo sapiens scaffold attachment factor A (SAF-A)
41 HSBTRCP Homo sapiens mRNA for beta-transducin repeat containing protein
42 AF110763 Homo sapiens skeletal muscle LIM-protein 1 (FHL1) gene
43 HUMHO2SOS1 Human mRNA for heme oxygenase-2
44 HSHMSH16 Human mutator hMSH2 gene
45 HSEHK1 Homo sapiens mRNA for EHK-1 receptor tyrosine kinase
46 HSKLON30 Homo sapiens mRNA for unknown antigen
47 AB005047 Homo sapiens mRNA for SH3 binding protein
48 AF070561 Homo sapiens clone 24703 beta-tubulin
49 HUMCAM1V Human vascular cell adhesion molecule 1
50 HSRNASMG Homo sapiens mRNA for Sm protein G
51 X83228 Homo sapiens mRNA for LI-cadherin
52 AF125100 Homo sapiens HSPC039 protein
53 HSU97018 Homo sapiens echinoderm microtubule-associated protein homolog HuEMAP
54 HSU43188 Human Ets transcription factor (NERF-2)
55 HSY17392 Homo sapiens mRNA for prefoldin subunit 1
56 HSU08316 Human insulin-stimulated protein kinase 1 (ISPK-1)
57 HZNF232G2 Homo sapiens zinc finger protein ZNF232, exons2 and 3
58 HUMP53T Human p53 cellular tumor antigen
59 J03040 Human SPARC/osteonectin
60 XM_053809 Homo sapiens similar to chondroitin sulfate proteoglycan 2 (versican)
61 L40379 Homo sapiens thyroid receptor interactor (TRIP10)
62 HSU72069 Human karyopherin beta2
63 HUMPGK2 Human phosphoglycerate kinase (pgk) mRNA, exons 2 to last
64 HSU07139 Human voltage-gated calcium channel beta subunit
65 XM_001472 Homo sapiens v-jun sarcoma virus 17 oncogene homolog (avian) (JUN)
66 AU100088 Human phosphogluconate dehydrogenase (hPGDH) gene
67 HUMKRUPZN Human Kruppel related zinc finger protein (HTF10)
68 AF077050 Homo sapiens neuroendocrine-specific protein C homolog
69 HUMSC35A Human splicing factor SC35
70 HUMPTPB Homo sapiens protein tyrosine phosphatase (CIP2)
71 AF049608 Homo sapiens monocarboxylate transporter 2 (MCT2)
72 HUMHEK Human receptor tyrosine kinase (HEK)
73 J03210 Human collagenase type IV
74 HSRAB9P40 Homo sapiens mRNA for Rab9 effector p40
75 AF184924 Homo sapiens zinc finger transcription factorBTEB2 gene
76 HUMC5A2A Human fibrillar collagen (proa2 (V)) gene
77 HUMGAPA Human GTPase-activating protein ras p21 (RASA)
78 HUMGLURS Human glutamate receptor subunit (GluH1)
79 AF047715 Homo sapiens A-kinase anchoring protein (AKAP18)
80 HSU40282 Homo sapiens integrin-linked kinase (ILK)
81 HSATPF1M Human mRNA for mitochondrial ATP synthase(F1-ATPase) alpha subunit
82 AF152485 Homo sapiens protocadherin alpha 7 short formprotein (PCDH-alpha7)
83 HSRP19 Human mRNA for 19 ku protein of signal recognition particle (SRP)
84 U17195 Homo sapiens A-kinase anchor protein (AKAP100)
85 HSU79299 Human neuronal olfactomedin-related ER localizedprotein
86 XM_037859 Human focal adhesion kinase (FAK)
87 HSU04209 Human-associated microfibrillar protein
88 D82878 Hemicentrotus pulcherrimus mRNA for p34cdc2
89 AF060515 Homo sapiens cyclin K (CPR4)
90 D21262 Human mRNA for KIAA0035 gene
91 NM_005641 Homo sapiens TATA box binding protein-associatedfactor, RNA polymerase II, 85 ku
92 HSU07550 Human chaperonin 10
93 X82153 Homo sapiens mRNA for cathepsin 0
94 HSU41766 Human metalloprotease/disintegrin/cysteine-richprotein precursor (MDC9)
95 AB017019 Homo sapiens mRNA for JKTBP2
96 HUMFNC Human cellular fibronectin
97 U93033 Homo sapiens thyroglobulin (TG)
98 AF0304354 Homo sapiens proteoglycan 3 (PRG3) gene
99 HUMCOL3IX Homo sapiens collagen alpha 3 type IX (COL9A3)
100 NM_002427 Homo sapiens matrix metalloproteinase 13(MMP13)
101 AF039747 Homo sapiens cadherin-10 (CDH10)
102 AF072242 Homo sapiens methyl-CpG binding protein MBD2(MBD2)
103 HSMYCC Human c-myc oncogene
104 HSTSPM Homo sapiens tissue specific mRNA
105 HSU64317 Human Crk-associated substrate relatedprotein Cas-L
106 HSVACM1 Homo sapiens mRNA for vasopressin activatedcalcium mobilizing receptor-like protein
107 HUMPA1V Human pro-alpha-1 (V) collagen
108 AF059611 Homo sapiens nuclear matrix protein NRP/B (NRPB)
109 HSU004845 Human a6 (I V) collagen (COL4A6)
110 M87860 Human S-lac lectin L-14-II (LGALS2) gene
111 AF492837 Human mRNA for osteopontin
112 HSCOX7BM Homo sapiens coxVIIb mRNA for cytochromec oxidase subunit VIIb
113 U01244 Human fibulin-1D
114 U52153 Human inwardly rectifying potassium channelKir3.2
115 S66427 RBP1=retinoblastoma binding protein 1 [human, Nalm-6 pre-B cell leukemia, mRNA, 4834 nt]
116 AF117108 Homo sapiens IGF-II mRNA-binding protein3 (IMP-3)
117 HSU49083 Human cell surface heparin binding protein HIP
118 HSU59289 Human H-cadherin
119 HSU95032 Human growth-arrest-specific protein 2
120 HSU18018 Human E1A enhancer binding protein (E1A-F)
121 HUMCGRPB Homo sapiens (clone HSNME29) CGRP type1 receptor
122 X59543 Human mRNA for M1 subunit of ribonucleotidereductase
123 AF072810 Homo sapiens transcription factor WSTF
124 AF005068 Homo sapiens breast and ovarian cancersusceptibility protein splice variant (BRCA1)
125 HSU66197 Human fibroblast growth factor homologous factor1 (FHF-1)
126 HUMVTNR Human cell adhesion protein (vitronectin) receptoralpha subunit
127 HSA6417 Homo sapiens mRNA for beta-tubulin foldingcofactor D
128 AF109126 Homo sapiens stromal cell-derived receptor-1 beta
129 AB030078 Homo sapiens mRNA for K-sam-II03
130 HUMMFAP Homo sapiens extracellular matrix protein (MFAP3)gene
131 HUMCOLVA Human alpha-2 type V collagen gene
132 HUMAAMP1X Homo sapiens angio-associated migratory cell protein (AAMP)
133 Y08319 Homo sapiens mRNA for kinesin-2
134 HSVWFR1 Human mRNA for pre-pro-von Willebrand factor
135 S60085S2 ADMLX=putative adhesion molecule [human,mRNA, 4121 nt, segment 2 of 2]
136 HSU51334 Homo sapiens signal transducing adaptor molecule 2A (STAM2)
137 AF435957 Homo sapiens Ly-6 antigen/uPA receptor-likedomain-containing protein
138 NM_000245 Homo sapiens met proto-oncogene (hepatocytegrowth factor receptor)
139 XM_044659 Homo sapiens c-src tyrosine kinase (CSK)
140 AF061573 Homo sapiens protocadherin (PCDH8)
141 HUMMFAP Homo sapiens extracellular matrix protein (MFAP3)gene
142 AF081535 Homo sapiens CDC45L (CDC45L)
143 HUMCA1XIA Human alpha-1 type XI collagen (COL11A1)
144 AB016625 Homo sapiens OCTN2 gene
145 AF151899 Homo sapiens CGI-141 protein
146 HSU12535 Human epidermal growth factor receptor kinasesubstrate (Eps8)
147 HSFCRIB Human mRNA for high affinity Fc receptor (FcRI) 慴 form’
148 HSU74628 Homo sapiens cell division control related protein (hCDCrel-1)
149 AF039564 Homo sapiens retinoblastoma binding protein (RBBP9)
150 HUMGAPA Human GTPase-activating protein ras p21 (RASA)
151 HUMSTK2A Human protein serine/threonine kinase stk2
152 AF144700 Homo sapiens small zinc finger-like protein (TIM13)
153 HUMTUBAK human alpha-tubulin
154 HUMADCY Homo sapiens adenyl cyclase-associated protein (CAP)
155 HSU89329 Human alternatively spliced microtubule-associatedprotein 2C (MAP2)
156 BC00051 Homo sapiens, Insulin-like growth factor 2
157 HSU89329 Human alternatively spliced microtubule-associated protein 2C (MAP2)
158 BC00051 Homo sapiens, insulin-like growth factor 2
159 AB000529 Homo sapiens, prostate differentiation factor
160 HSMAP01 Human microtuble-associated protein-2 (MAP-2) gene, exon 1
161 X67951 Human mRNA for proliferation-associated gene (pag)
162 M94250 Human retinoic acid inducible factor (MK) gene
163 XM_046278 Homo sapiens core promoter element binding protein (COPEB)
164 HSBM40 Human mRNA for extracellular matrix protein BM-40
165 HSU76381 Homo sapiens fibroblast growth factor (FGF-12b)
166 HSCALM2S04 Homo sapiens calmodulin (CALM2) gene, exons 3-6
167 HUMID2X Human helix-loop-helix protein(ID-2)
168 U20758 Human osteopontin gene
169 AF152307 Homo sapiens protocadherin alpha 11(PCDH-alpha11)
170 HUMAAMP1X Homo sapiens angio-associated migratory cell protein (AAMP)
171 HUMMXI1A Human MXI1
172 AF143536 Homo sapiens colon cancer-associated protein Mic1(MIC1)
173 HSU70322 Human transportin (TRN)
174 HUMMNMP Human major nuclear matrix protein
175 AF071057 mRNA differentially expressed in GC7901 and GES-1
176 AF219140 Homo sapiens gastric cancer-related protein GCYS-20
177 HSU40282 Homo sapiens integrin-linked kinase (ILK)
178 HSCA2VR Human mRNA for pro-alpha 2 (V) collagen chain
179 HUMPECAM27 Homo sapiens platelet/endothelial cell adhesion molecule-1 (PECAM-1) gene
180 XM_165823 Homo sapiens tumor necrosis factor (TNF superfamily, member 2) (TNF)
181 D21063 Homo sapiens MCM2 minichromosome maintenance deficient 2, mitotin
182 XM_168045 Homo sapiens CD24 antigen (small cell lung carcinoma cluster 4 antigen) (CD24)
183 XM_030326 Homo sapiens CD44 antigen (CD44)
184 XM_034862 Homo sapiens interferon regulatory factor 1 (IRF1)
185 AB025106 Homo sapiens mRNA for E-cadherin
186 U73704 Homo sapiens 48 ku FKBP-associated protein FAP48
187 AF380298 Oncorhynchus mykiss interferon regulatory factor 1 gene, promoter region and partial sequence
188 L24203 Homo sapiens ataxia-telangiectasia group D-associated protein
189 D45906 Homo sapiens mRNA for LIMK-2
190 D21255 Human mRNA for OB-cadherin-2
191 X54925 Homo sapiens mRNA for type I interstitial collagenase
192 X05232 Human mRNA for stromelysin, matrix metalloproteinase 3
193 M22612 Human pancreatic trypsin 1 (TRY1)
194 HUMGOS8PPC Human helix-loop-helix basic phosphoprotein (GOS8)
195 HUMTHBS3 Homo sapiens thrombospondin 3 (THBS3) gene
196 HSVECAD Homo sapiens VE-cadherin
197 HSBTRCP Homo sapiens mRNA for beta-transducin repeat containing protein
198 HUMPROFII Human profilin II
199 HSCALT Homo sapiens mRNA for caltractin
200 AF091214 Homo sapiens WRN (WRN)
201 AF070561 Homo sapiens clone 24703 beta-tubulin
202 HUMCD14MCA Human monocyte antigen CD14 (CD14)
203 HUMCAM1V Human vascular cell adhesion molecule 1
204 AF032900 Homo sapiens timing protein CLK-1
205 AF070561 Homo sapiens clone 24703 beta-tubulin
206 HSUPUE Homo sapiens mRNA for unknown protein of uterine endometrium
207 HUMIL8RB Homo sapiens interleukin 8 receptor beta (IL8RB)
208 HSERK3 Homo sapiens ERK3
209 AF208045 Homo sapiens breast cancer-associated antigen BRCAA1 (BRCAA1)
210 AF081259 Homo sapiens testis-specific chromodomain Y-like protein (CDYL)
211 AB022918 Homo sapiens mRNA for alpha2,3-sialyltransferaseST3Gal VI
212 AF057036 Homo sapiens acetylcholinesterase collagen-like tail subunit (COLQ)
213 AF152497 Homo sapiens protocadherin beta 4 (PCDH-beta4)
214 M86752 Stress-induced phosphoprotein 1
215 L04270 TNF C receptor
216 AF009674 Axin 1
Highly expressed genes in precancerous lesions
1 HSU72621 Human LOT1
2 HUMNMOR Human NAD(P)H: menadione oxidoreductase
3 AF009227 Homo sapiens gamma-heregulin
4 HSU44839 Human putative ubiquitin C-terminal hydrolase(UHX1)
5 HUMAAE Homo sapiens dbpB-like protein
6 HSU08316 Human insulin-stimulated protein kinase 1 (ISPK-1)
7 HUMCD3621 Human antigen CD36 (clone 21)
8 Z11899 Homo sapiens OTF3 mRNA for encoding octamer binding protein 3B
9 XM_003226 Homo sapiens vasoactive intestinal peptide receptor 1 (VIPR1)
10 HUMPAI2B Human plasminogen activator inhibitor 2 (PAI-2)
11 HUMACTIIA Human activin type II receptor
12 M93718 Human nitric oxide synthase
13 HSU46837 Human RNA polymerase II holoenzyme componentSRB7 (SRB7)
14 HUMPCNA Human proliferating cell nuclear antigen (PCNA) gene
15 HSPCAR Human mRNA for calcium dependent protease(small subunit)
16 HSU12140 Human tyrosine kinase receptor p145TRK-B(TRK-B)
17 HSTOP2A10 Homo sapiens topoisomerase II alpha (TOP2A) gene,exons 34 and 35
18 HUMYWXD703 Homo sapiens ADP/ATP carrier protein (ANT-2)gene
19 HUMKGF Human keratinocyte growth factor
20 HS40KDAP Homo sapiens 40 ku protein kinase related to ratERK2
21 HUMPAFAA Human mRNA for platelet activating factoracetylhydrolase IB gamma-subunit
22 HUMLPL Human lipoprotein lipase
23 HUMMYLCC Human smooth muscle myosin alkali light chain (MLC 1sm)
24 HSU10564 Human CDK tyrosine 15-kinase WEE1Hu (Wee1Hu)
25 AF022655 Homo sapiens cep250 centrosome associated protein
26 D49737 Homo sapiens mRNA for cytochrome b large subunitof complex II
27 HUMCD53GLY Human CD53 glycoprotein
28 L02867 Homo sapiens 62 ku paraneoplastic antigen
29 HUMCALBETB Human voltage-dependent calcium channel beta-1subunit
30 HUMEPSURAN Human surface antigen
31 AB020647 Homo sapiens mRNA for KIAA0840 protein
32 HSU88966 Human protein rapamycin associated protein(FRAP2) gene
33 HUMHGLUT1 Human mRNA for glutamate transporter
34 U70663 Human zinc finger transcription factor hEZF(EZF)
35 HSPTS1R Homo sapiens mRNA for peroxisomal targetingsignal 1 (SKL type) receptor
36 HSU61276 Human transmembrane protein Jagged 1 (HJ1)
37 HUMMYONM Human nonmuscle myosin heavy chain (NMHC)
38 AF016270 Homo sapiens thyroid hormone receptor coactivating protein
39 HSU66243 Human p38 gamma MAP Kinase
40 HSU41766 Human metalloprotease/disintegrin/cysteine-richprotein precursor (MDC9)
41 HUMELF2 Human translational initiation factor 2 beta subunit(elF-2-beta)
42 HUMCYCAA Human somatic cytochrome c (HCS) gene
43 NM_013217 Homo sapiens gene for AF-6
44 AB017642 Homo sapiens mRNA for oxidative-stress responsive 1
45 AF110956 Homo sapiens SUMO-1 activating enzyme subunit 1
(SAE1)
46 HUMALR Human aldehyde reductase
47 HUMATPSAS Human gene for ATP synthase alpha subunit (exon1 to 12)
48 AF052497 Homo sapiens clone B18
49 AB000889 Homo sapiens mRNA for phosphatidic acidphosphatase 2b
50 HUMTPARN Homo sapiens mRNA for tissue plasminogen activator.
51 AF006082 Homo sapiens actin-related protein Arp2 (ARP2)
52 HSU21090 Human DNA polymerase delta small subunit
53 HUMVENHK1 Human voltage-gated potassium channel (HK1)
54 HUMVTNR Human cell adhesion protein (vitronectin) receptoralpha subunit
55 AF091242 Homo sapiens ATP sulfurylase/APS kinase 2
56 HUMIGFBP1 Human insulin-like growth factor binding protein-1 (IGFBP1) gene
57 AF047439 Homo sapiens unknown
58 AF117386 Homo sapiens ubiquitin-specific protease (UBP)
59 AF092129 Homo sapiens guanine nucleotide binding protein gamma-3 subunit
60 HUMCOXIV Human cytochrome c oxidase COX subunit IV(COX IV)
61 J05412 Human regenerating protein (reg) gene
62 AF054162 Gccys-1, mRNA differentially expressed betweenGC7901 and GES-1
63 AF054163 Gccys-2, mRNA differentially expressed betweenGC7901 and GES-1
64 AF054164 Gccys-3,mRNA differentially expressed betweenGC7901 and GES-1
65 AF054165 Gccys-4, mRNA differentially expressed betweenGC7901 and GES-1
66 AF054166 Gccys-5, mRNA differentially expressed betweenGC7901 and GES-1
67 AF054167 Gccys-6, mRNA differentially expressed betweenGC7901 and GES-1
68 NM_003542 Homo sapiens H4 histone family, member G(H4FG)
69 XM_032781 Homo sapiens tubulin, gamma 1 (TUBG1)
70 XM_083852 Homo sapiens ribonucleotide reductase M1polypeptide(RRM1)
71 HSU51586 Human siah binding protein 1 (siahBP1)
72 X55181 Human ETS2 gene
73 NM_004526 Homo sapiens MCM2 minichromosomemaintenance deficient 2, mitotin (MCM2)
74 XM_040900 Homo sapiens MAP/microtubule affinity-regulatingkinase 3 (MARK3)
75 XM_083852 Homo sapiens ribonucleotide reductase M1polypeptide(RRM1)
76 NM_012145 Homo sapiens deoxythymidylate kinase(thymidylate kinase) (DTYMK)
77 X59543 Ribonucleotide reductase M1 polypeptide
78 M74542 Human aldehyde dehydrogenase type III (ALDHIII)
79 M61855 Human cytochrome P4502C9 (CYP2C9)
80 S37730 Homo sapiens insulin-like growth factor bindingprotein-2
81 AB015982 Homo sapiens EPK2 mRNA for serine/threoninekinase
82 X67951 Human mRNA for proliferation-associated gene(pag)
83 AF127506 Homo sapiens adenomatosis polyposis coli tumorsuppressor (APC) gene
84 HT880 Human Gastric mucin 6
85 M63154 Gastric intrinsic factor
Highly expressed genes in normal gastric mucous
1 X05997 Human mRNA for gastric Lipase
2 U75272 Human gastricsin
3 M63154 Human intrinsic factor
4 AF043909 Homo sapiens gastric mucin (MUC5AC)
5 L07518 Homo sapiens mucin
6 M61853 Human cytochrome p4502C18 (CYP2C18)
7 M10942 Human metallothionein-Ie gene (hMT-Ie)
8 L15533 Homo sapiens pancreatitis-associated protein (PAP)gene
9 Z49107 Homo sapiens galectin
10 U52191 Human SMCY (H-Y)
11 NM_005522 Homo sapiens homeo box A1 (HOXA1)
12 M57732 Human hepatic nuclear factor 1 (TCF1)
13 X59770 Homo sapiens IL-1R2 mRNA for type II interleukin-1 receptor
14 X76223 Homo sapiens MAL gene exon 4
15 U05259 Human MB-1 gene
16 XM_052013 Homo sapiens polymeric immunoglobulin receptor(PIGR)
17 U90065 Human potassium channel KCNO1
18 M55422 Human Krueppel-related zinc finger protein (H-plk)
19 S78825 Id1, transcription regulator helix-loop-helix protein
20 U19948 Human protein disulfide isomerase (PDIp)
21 U43522 Human cell adhesion kinase beta (CAKbeta)
22 U12139 Human alphal (XI) collagen (COL11A1) gene, 5region and exon 1
23 M14539 Human factor XIII subunit
24 X65614 Homo sapiens mRNA for calcium-binding proteinS100P
25 AF000560 Homo sapiens TTF-I interacting peptide 20
26 AF002224 Homo sapiens Angelman Syndrome Gene, E6-APubiquitin protein ligase 3A
27 U57096 Human janus kinase 3 (Jak3)
28 U42600 Human calcium-activated potassium channel betasubunit
29 NM_017406 cAMP responsive element binding protein-like 1
30 U04806 Human FLT3/FLK2 ligand
31 D84361 Human p52 and p64 isoforms of N-Shc
32 Z30425 Homo sapiens orphan nuclear hormone receptor
33 M16364 Human creatine kinase-B
34 X96924 Homo sapiens encoding mitochondrial citratetransport protein
35 HSNM23H1 Homo sapiens nm23H1 gene
36 NM_014792 Homo sapiens KIAA0125 gene product (KIAA0125)
37 M34041 Human alpha-2-adrenergic receptor (aipha-2 c2) gene
38 XM_002444 Homo sapiens serine threonine kinase 39 (Stk39)
39 NM_001690 Homo sapiens ATPase, H+ transporting, lysosomal70 ku, V1 subunitA
40 L12398 Human sapiens dopamine receptor D4 (DRD4)
41 L76465 Homo sapiens NAD+ dependent 15hydroxyprostaglandin dehydrogenase (PGDH)
42 U57094 Human small GTP-binding protein
43 Z14978 Homo sapiens mRNA for actin-related protein
44 X53961 Human lactotransferrin
45 M62628 Human alpha-1 Ig germline C-region membrane-coding region
46 M84526 Human adipsin/complement factor D
47 X04391 Human lymphocyte glycoprotein T1/Leu-1
48 X044533 Homo sapiens sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) andshort cytoplasmic domain, (semaphoring) 4B(SEMA4B)
49 AF071054 Gcys-11, mRNA differentially expressed in cell linesGC7901 and GES-1
50 AF063015 Homo sapiens cell division protein
51 AF071056 Gcys-17, mRNA differentially expressed in cell lines GC7901 and GES-1
52 AF071058 Gcys-15, mRNA differentially expressed in cell lines GC7901 and GES-1
53 NM_001730 Homo sapiens Kruppel-like factor 5 (intestinal)(KLF5), mRNA
54 AB047278 Arabidopsis thaliana AtNdr 1 mRNA for Ndr kinase
55 XM_061005 Homo sapiens similar to Mucin 2 precursor(Intestinal mucin2)
56 HUM20D9 Human gene for 2-oxoglutarate dehydrogenase
57 HSCDC2 Human CDC2 gene involved in cell cycle control
58 AF202051 Homo sapiens NM23-H8 (NME8)
59 NM_005423 Homo sapiens trefoil factor 2 (spasmolytic protein 1) (TFF2)
60 D50419 Homo sapiens OTK18
61 HSU88870 Human cell division control-related protein 2b(hcdcrel2b)
62 NM_031942 Homo sapiens cell division cycle associated 7(CDCA7)
63 HSU09716 Human mannose-specific lectin (MR60)
64 HSU14394 Human tissue inhibitor of metalloproteinases-3
65 Z48314 Apomucin
66 M63154 Gastric intrinsic factor
67 J05412 Regenerating protein
68 M57732 Hepatic nuclear factor 1
69 U70663 Kruppel-like factor 4
70 AB002559 Syntaxin binding protein 2
71 U80226 GABA transaminase
72 U05259 CD79A
73 X04391 CD5
74 U60800 CD100
75 M74542 Aldehyde dehydrogenase 3
76 X66839 Carbonic anhydrase IX
77 L00972 Cystathionine-beta-synthase
78 L41688 UDP-galactose-4 epimerase
79 J03915 Chromogranin A
80 S76942 Dopamine receptor D4
81 D14695 Herp
82 D50915 D50915
83 D86961 HMGIC fusion partner-like 2
84 X96924 Mitochondrial citrate transporter
85 M16364 Creatine kinase, brain
86 M14539 Factor XIII precursor
87 U19948 Protein disulfide isomerase
88 X65614 S100 calcium binding protein P
Highly expressed genes associated with metastasis
1 NM_004994 Homo sapiens matrix metalloproteinase 9(gelatinase B, 92 ku type IV collagenase) (MMP9)
2 XM_053256 Homo sapiens mucin 1, transmembrane (MUC1)
3 XM_010702 Homo sapiens cathepsin K (pycnodysostosis) (CTSK)
4 NM_002628 Homo sapiens profiling 2 (PFN2), transcript variant 2
5 NM_002128 Homo sapiens high-mobility group protein 1 (HMG1)
6 M28130 Human interleukin 8 (IL8) gene
7 S3488 Metastasis-associated gene (human, highlymetastatic lung cell subline Anip)
8 NM_005231 Homo sapiens ems1 sequence, transcript variant 1
9 XM_059020 Homo sapiens similar to GPI-anchored metastasis-associated protein homolog
10 NP_571483 Vascular endothelial growth factor (VEGF)
11 I56986 OPN-a-human (fragment)
12 AAG31602 CD44 isoform v3-v6
13 AF018733 92 ku type IV collagenase precursor (matrixmetalloproteinase-9) (MMP-9)
14 AF00196 Octamer-binding transcription factor 2 (OTF-2)
15 XM_055254 Homo sapiens fibronectin 1 (FN1)
Risk factor genes
1 V01555 Epstein-Barr virus (EBV) genome, strain B95-8
2 AF275307 H pylori plasmid pHPM8 (cagA)
3 AF275307 H pylori plasmid vacA
4 AF275307 H pylori plasmid Urase
5 AF431736 Human herpesvirus 1 strain KOS ICPO gene
6 Z86099 Herpes simplex virus type 2 (strain HG52)
7 AF477385 Human papillomavirus type 16 E7 gene
8 AX742207 Human hepatitis virus 11 type