Table 1.
Groups |
n |
Weight of tumor (g) |
IR (%) |
|||
Exp 1 | Exp 2 | Exp 1 | Exp 2 | Exp 1 | Exp 2 | |
Lecithin control | 14 | 14 | 1.39±0.70 | 1.42±0.41 | 0 | 0 |
NS control | 13 | 14 | 1.49±0.80 | 1.41±0.46 | 0 | 0 |
CDDP d1-5 | 14 | 13 | 0.68±0.27 | 0.81±0.30 | 54 | 43 |
CDDP d6-10 | 12 | 14 | 0.80±0.25 | 0.96±0.32 | 46 | 32 |
Gefitinib d1-10 | 14 | 0.88±0.28 | 41 | |||
Gefitinib d1-5 | 14 | 0.99±0.39 | 30 | |||
Gefitinib d1-10+CDDP d1-5 | 13 | 0.66±0.24 | 56 | |||
Gefitinib d1-10+CDDP d6-10 | 14 | 1.11±0.41b | 26b | |||
Gefitinib d1-5+CDDP d1-5 | 14 | 0.63±0.35 | 56 | |||
CDDP d1-5→Gefitinib d6-10 | 13 | 0.55±0.25b | 61b | |||
Gefitinib d1-5→CDDP d6-10 | 13 | 0.90±0.30 | 36 |
P<0.01 vs Gefitinib d1-10+CDDP d1-5, or Gefitinib d1-5→CDDP d6-10 group, IR: inhibitory rate, CDDP: cisplatin, Exp 1: the first experiment, Exp 2: the second experiment.