Table 3.
HBsAg and HBV DNA secreted into cell culture medium with or without IFN (mean±SD).
| Recombinants |
HBsAg (A450) |
HBV DNA (realtime PCR, log10) |
||
| Without IFN | With IFN | Without IFN | With IFN | |
| Puc18-HBV1.2-WT | 2.63±0.1c | 1.96±0.07c | 5.02±0.06ac | 4.86±0.07c |
| Puc18-HBV1.2-A1896 | 1.43±0.05 | 1.46±0.07 | 4.43±0.09ac | 5.53±0.07c |
| Puc18-HBV1.2-A1899 | 1.97±0.15 | 1.96±0.12 | 4.80±0.05 | 4.90±0.06 |
| Puc18-HBV1.2-AA | 2.6±0.05 | 2.5±0.06 | 4.06±0.07ac | 4.46±0.05c |
n = 3,
a
P<0.05 (WT in comparison with MT without IFN),
c
P<0.05 (without IFN in comparison with with IFN). WT: wild type, MT: mutated type.