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. 2005 Jan 28;11(4):538–544. doi: 10.3748/wjg.v11.i4.538

Table 7.

Histological scoring (effect of PACAP receptor antagonists) (mean±SE).

Group Hemorrhage Parenchymal necrosis Vacuolization Inflammatory infiltration
Caerulein-induced pancreatitis 1.67±0.60 2.5±0.22
Sodium taurocholate-induced pancreatitis 1.5±0.67 2.5±0.49 0.5±0.49 3
10 μg PACAP6-27 1.5±0.5
100 μg PACAP6-27 0.83±0.54
Caerulein+10 μg PACAP6-27 0.83±0.54 0.17±0.17 1.83±0.60 2.5±0.5
Caerulein+100 μg PACAP6-27 1.67±0.49 1±0.52 2.17±0.31 2.5±0.22
Sodium taurocholate+10 μg PACAP6-27 1.5±0.67 3 1.33±0.61 3
Sodium taurocholate+100 μg PACAP6-27 1.5±0.5 2.83±0.17 2±0.52 3
10 μg (4-Cl-D-Phe6, Leu17) VIP 0.33±0.33 2±0.63
100 μg (4-Cl-D-Phe6, Leu17) VIP 1±0.63 1.67±0.60
Caerulein+10 μg (4-Cl-D-Phe6, Leu17) VIP 0.17±0.17 0.17±0.17 0.67±0.40 2±0.51
Caerulein+100 μg (4-Cl-D-Phe6, Leu17) VIP 0.33±0.33 1.67±0.49 2.17±0.48
Sodium taurocholate+10 μg (4-Cl-D-Phe6, Leu17) VIP 1.5±0.56 2.5±0.49 1.17±0.60 3
Sodium taurocholate+100 μg (4-Cl-D-Phe6, Leu17) VIP 1.5±0.67 2.33±0.33 1.83±0.60 3