FIG. 2.

Individual serum bile acid levels were measured in control patients and in patients with APAP-induced ALF at peak ALT time for each patient (A), which were grouped into survivors (S) and non-survivors (NS). GDCA was found to be significantly increased in non-survivors (B) and was associated with a moderate predictive value by ROC analysis (C). Glycine conjugates and taurine conjugates of each bile acid were totaled and averaged for each patient (D). N for each group is indicated in Table 1. *P < 0.05 versus matched pair.