Table 2.

Comparison between TLC SF-36 Scores and US norms

SF-36 measure	US norm	TLC (n=264)	p-value*	Effect size#	US patients only	p-value	Effect size#
Physical Functioning	50	48.18*	0.004	0.18	49.32	0.35	0.068
Role-Physical	50	47.33*	<0.0001	0.27 (small)	48.52*	0.042	0.15
Bodily Pain	50	49.41	0.35	0.059	50.19	0.80	−0.019
General Health	50	41.5*	<0.0001	0.85 (large)	41.27*	<0.0001	0.87 (large)
Vitality	50	48.89	0.08	0.11	49.65	0.63	0.035
Social Functioning	50	46.79*	<0.0001	0.32 (small)	48.01*	0.006	0.20
Role-Emotional	50	46.78*	<0.0001	0.32 (small)	48.15*	0.01	0.18
Mental Health	50	49.04	0.12	0.096	49.38	0.40	0.062
Physical Summary	50	46.8*	<0.0001	0.32 (small)	47.57*	<0.0001	0.24 (small)
Mental Summary	50	47.95*	0.002	0.20	48.73	0.11	0.13

^*one sample T test shows significant difference between population and US norm (p<0.05)

^#effect size = difference in mean / population SD

Clinically significant effects defined as: 0.2-0.49 = ‘small’, 0.50-0.79 = ‘moderate’, >0.80 = ‘large’(8)