Table 2. Correlation between expressions of PTEN and Ki67 in NSCLC with clinicopathologic features.
N | PTEN |
Ki67 |
||||||||
+ | - | Positive expression (%) | P-value | + | - | Positive expression (%) | P-value | |||
Age (years) | ||||||||||
≤60 | 30 | 11 | 19 | 36.67 | 0.548 | 21 | 9 | 70.00 | 0.290 | |
> 60 | 37 | 11 | 26 | 29.73 | 30 | 7 | 81.08 | |||
Sex | ||||||||||
Male | 33 | 10 | 23 | 30.30 | 0.664 | 26 | 7 | 78.79 | 0.614 | |
Female | 34 | 12 | 22 | 35.29 | 25 | 9 | 73.53 | |||
Tumor position | ||||||||||
Periphery type | 40 | 10 | 30 | 25.00 | 0.096 | 31 | 9 | 77.50 | 0.747 | |
Central type | 27 | 12 | 15 | 44.44 | 20 | 7 | 74.07 | |||
Tumor size (cm) | ||||||||||
≤3 | 35 | 13 | 22 | 37.14 | 0.432 | 24 | 11 | 68.57 | 0.130 | |
> 3 | 32 | 9 | 23 | 28.13 | 27 | 5 | 84.38 | |||
Tumor category | ||||||||||
Squamous cancer | 28 | 5 | 23 | 18.71 | 19 | 9 | 67.9 | |||
Adenocarcinoma | 31 | 12 | 19 | 38.70 | 0.014 | 25 | 6 | 80.65 | 0.037 | |
Large cell carcinoma | 8 | 3 | 5 | 37.50 | 5 | 3 | 62.50 | |||
Lymph metastasis | ||||||||||
Yes | 29 | 5 | 24 | 17.24 | 0.018 | 31 | 9 | 77.5 | 0.023 | |
No | 38 | 17 | 21 | 44.74 | 8 | 9 | 47.0 | |||
TNM Stage | ||||||||||
I,II | 49 | 22 | 27 | 44.90 | 0.038 | 30 | 19 | 61.22 | 0.043 | |
III | 18 | 6 | 12 | 33.33 | 14 | 4 | 77.8 | |||
Differentiation degree | ||||||||||
Low | 25 | 5 | 20 | 20.00 | 0.007 | 23 | 2 | 92.00 | 0.020 | |
High/moderate | 42 | 19 | 23 | 45.24 | 28 | 14 | 66.67 |